Tags: cattle, injection, mgml, retail, solution, zuprevo
Zuprevo 180 mg/ml solution for injection for cattle. Qualitative and quantitative composition. Active substance One ml contains: Tildipirosin 180 mg. For a full list of excipients, see section Pharmaceutical particulars. For the treatment and prevention of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni sensitive to tildipirosin. The presence of the disease in the herd should be confirmed before preventive treatment. Do not use in case of hypersensitivity to macrolide antibiotics or to any of the excipients. Special warnings for each target species. Special precautions for use. Whenever possible, the veterinary medicinal product should only be used based on susceptibility testing. Official, national and regional antimicrobial policies should be taken into account when the product is used. Tildipirosin may cause sensitisation by skin contact. If accidental skin exposure occurs, wash the skin immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with clean water. Wash hands after use. Special caution should be taken to avoid accidental self-injection, as toxicology studies in laboratory animals showed cardiovascular effects after intramuscular administration of tildipirosin. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. Do not use in automatically powered syringes which have no additional protection system. Pain on injection and injection site swellings are very common in treated animals. Following the maximum recommended injection site volume of 10 ml, injection site swellings may be associated with pain on palpation for about one day in individual animals. The swellings are transient and will usually resolve within 7 to 16 days; in individual animals swellings may persist for 21 days. Pathomorphological injection site reactions will largely resolve within 35 days. Use during pregnancy, lactation or lay. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. However, there was no evidence for any selective developmental or reproductive effects in any of the laboratory studies. Use only according to the benefit/risk assessment by the responsible veterinarian. There is cross resistance with other macrolides. Do not administer with antimicrobials with a similar mode of action such as other macrolides or lincosamides. Amounts to be administered and administration route. Administer 4 mg tildipirosin/kg body weight (equivalent to 1 ml/45 kg body weight) once only. For treatment of cattle over 450 kg body weight, divide the dose so that no more than 10 ml are injected at one site. The rubber stopper of the vial may be safely punctured up to 20 times. Otherwise, the use of a multiple-dose syringe is recommended. To ensure correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing. It is recommended to treat animals in the early stages of the disease and to evaluate the response to treatment within 2 to 3 days after injection. If clinical signs of respiratory disease persist or increase, treatment should be changed using another antibiotic, and continued until clinical signs have resolved. In calves, a single subcutaneous injection of 10 times the recommended dose (40 mg/kg body weight) and repeated subcutaneous administration of tildipirosin (on three occasions in intervals of 7 days) at 4, 12 and 20 mg/kg (1, 3 and 5 times the recommended clinical dose) were well tolerated, apart from transient clinical signs attributed to injection site discomfort and injection site swellings associated with pain in some animals. Cattle (Meat and offal): 47 days. The item “Zuprevo 180 mg/ml solution for injection for cattle 250 ml // Retail 1138 $” is in sale since Wednesday, February 12, 2020. This item is in the category “Business & Industrial\Agriculture & Forestry\Livestock Supplies\Animal Health & Veterinary”. The seller is “vetbargain” and is located in Tallinn. This item can be shipped to United States.
- Brand: Msd