Cydectin POUR-ON 500 ml Beef Dairy Cattle Dewormer Zero Slaughter Withdrawal. (Moxidectin) Ready to use topical formulation for control of roundworms, lungworms, grubs, lice and mites in cattle. Also provides 7 days of persistent activity against horn flies. No slaughter or milk withdrawal. Not for use veal calves. Apply 1 ml for each 22 lbs. Of body weight along the top of back from the withers to tail head. Efficacy not affected by rainfall. Pour-On for Beef and Dairy Cattle. Contains 5 mg moxidectin/mL. For Treatment of Infections and Infestations Due to Internal and External Parasites of Beef and Dairy Cattle. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. If animals are likely to be reinfected following treatment, a strategic parasite control program should be established. Mode of Action: Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. CYDECTIN (moxidectin) Pour-On is specially formulated to allow moxidectin to be absorbed through the skin and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. Moxidectin binds selectively and with high affinity to glutamate-gated chloride ion channels which are critical to the function of invertebrate nerve and muscle cells. This interferes with neurotransmission resulting in paralysis and elimination of the parasite. Indications: CYDECTIN Pour-On when applied at the recommended dose level of 0.5 mg/2.2 lb (0.5 mg/kg) body weight is effective in the treatment and control of the following internal adult and fourth-stage larvae L. And external parasites of cattle. Adult and L. Psoroptes ovis Psoroptes communis. Management Considerations for External Parasites: For most effective external parasite control, CYDECTIN Pour-On should be applied to all cattle in the herd. Cattle entering the herd following this administration should be treated prior to introduction. Consult your veterinarian or a livestock entomologist for the most appropriate time to apply CYDECTIN Pour-On in your location to effectively control horn flies and external parasites. CYDECTIN Pour-On provides seven days of persistent activity against horn flies. For optimal control of horn flies, the product should be used as part of an integrated control program utilizing other methods to provide extended control. Persistent Activity: CYDECTIN Pour-On has been proven to effectively control infections and protect from reinfection with. For 14 days after treatment. For 28 days after treatment, and. For 42 days after treatment. Efficacy below 90% was observed in some. Persistent activity studies at 21 and 28 days posttreatment. Dosage: CYDECTIN (moxidectin) Pour-On is a ready-to-use topical formulation intended for direct application to the hair and skin in a narrow strip extending along the top of the back from the withers to the tailhead (see Figure 1). Due to the angular topline characteristic of most dairy breeds, it is recommended that all pour-on products be applied slowly to dairy cows. Apply to healthy skin avoiding any mange scabs, skin lesions, mud or manure. Treated cattle can be easily recognized by the characteristic purple color, which will remain for a short period of time after treatment. The recommended rate of administration is 1 mL for each 22 lb (10 kg) body weight which provides 0.5 mg moxidectin for each 2.2 lb (0.5 mg/kg) body weight. The table below will assist in the calculation of the appropriate volume of pour-on which must be applied based on the weight of animal being treated. Do not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance. Where to Apply CYDECTIN Pour-On. Use Conditions: Varying weather conditions, including rainfall, do not affect the efficacy of CYDECTIN Pour-On. Administration: CYDECTIN Pour-On is available in three convenient package styles designed for ease of administration and the number of cattle to be treated. Directions for use of each container type follow. (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles). Determine the weight of the animal, calculate the recommended volume of CYDECTIN Pour-On and locate the volume marker equivalent to this dose on the dosing chamber of the bottle. Remove the dosing chamber cap and squeeze the main chamber of bottle until the desired level of solution is present in the dosing chamber. Release pressure on the container to avoid further filling. Holding the dosing chamber as shown below, pour this. Squeeze-Measure-Pour System (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles). Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 L Bottles and 338 fl oz/10 L Cubetainer). These bottles are designed for use with the CYDECTIN (moxidectin) Pour-On applicators. Simply remove the transient cap and seal and replace with the vented cap. Attach the applicator feeder hose to the vented cap. Invert the container prior to use (2.5 L and 5 L containers only). Apply the recommended volume of CYDECTIN Pour-On evenly along the backline of the animal from the withers to the tailhead (see Figure 1). Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 L Bottles). Body Weight Lb (kg). Approved by FDA under NADA # 141-099.
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Comments Off | June 13th, 2023
